ELIQUIS inhibits free and clot-bound factor Xa, and prothrombinase activity.
ELIQUIS has no direct effects on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting factor Xa, ELIQUIS prevents thrombin generation and thrombus development.1
Adapted from Eriksson et al. 2011.3
Please click here to access the ELIQUIS Patient Information Leaflet.
DVT = Deep Vein Thrombosis
NVAF = Non-Valvular Atrial Fibrillation
PE = Pulmonary Embolism
TF = Tissue Factor
References