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AMPLIFY-EXT

ELIQUIS (apixaban) has demonstrated superior efficacy with a comparable major bleeding rate vs. placebo in patients receiving treatment for prevention of DVT / PE recurrence1

ELIQUIS is only licensed for prevention of recurrent DVT / PE at a dose of 2.5 mg BD.2

* In patients for whom there was clinical uncertainty about the benefit of continuing treatment. Prior to the study, all patients had been treated for 6–12 months with standard anticoagulant therapy or had completed treatment with ELIQUIS or enoxaparin / warfarin as participants in the AMPLIFY trial.1

Diagnosemethoden

ELIQUIS dosing for your patients with DVT / PE is simple: START twice daily, STAY twice daily2

Access further resources, including treatment guidelines, patient materials and downloadable supporting materials


Purple information icon ELIQUIS (apixaban) SmPC

Please click here to access the ELIQUIS SmPC.

Purple information icon ELIQUIS (apixaban) Patient Information Leaflet

Please click here to access the ELIQUIS Patient Information Leaflet.

AMPLIFY-EXT = Apixaban after the Initial Management of Pulmonary Embolism and Deep Vein Thrombosis with First-Line Therapy–Extended Treatment   
BD = Twice Daily   
CI = Confidence Interval   
DVT = Deep Vein Thrombosis   
ITT = Intention-To-Treat   
LMWH = Low Molecular Weight Heparin   
N = Total number of patients in either the ELIQUIS group or the placebo group   
n = Number of patients with event   
PE = Pulmonary Embolism   
RR = Relative Risk   
SmPC = Summary of Product Characteristics   
VTE = Venous Thromboembolic Events

Not all patients who start on ELIQUIS for acute DVT / PE will stay on ELIQUIS; some acute DVT / PE patients who receive treatment do not require treatment for the prevention of recurrent DVT / PE. Other patients may be prescribed ELIQUIS for the prevention of recurrent VTE after initial treatment for acute DVT / PE with another anticoagulant.2 This is a decision for the prescribing clinician together with patient involvement in the decision-making.

References

  1. Agnelli G et al. N Engl J Med 2013; 368: 699–708.
  2. ELIQUIS® (apixaban) Summary of Product Characteristics.